Publication

 

(In descending order, starting from 2024)

  1. Investigating the Cytosolic Delivery of Proteins by Lipid Nanoparticles Using the Chloroalkane Penetration Assay. J. Wang, S. Zhang, Y. Li, Q. Xu & J.A. Kritzer. Biochemistry (2024).
  2. Harnessing non-Watson-Crick’s base pairing to enhance CRISPR effectors cleavage activities and enable gene editing in mammalian cells. S. Gao, H. Guan, H. Bloomer, D. Wich, D. Song, J. Khirallah, Z. Ye, Y. Zhao, M. Chen, C. Xu, L. Liu & Q. Xu. Proc Natl Acad Sci U S A 121, e2308415120 (2024).
  3. A prime editor mouse to model a broad spectrum of somatic mutations in vivo. Z.A. Ely, N. Mathey-Andrews, S. Naranjo, S.I. Gould, K.L. Mercer, G.A. Newby, C.M. Cabana, W.M. Rideout, 3rd, G.C. Jaramillo, J.M. Khirallah, K. Holland, P.B. Randolph, W.A. Freed-Pastor, J.R. Davis, Z. Kulstad, P.M.K. Westcott, L. Lin, A.V. Anzalone, B.L. Horton, N.B. Pattada, S.L. Shanahan, Z. Ye, S. Spranger, Q. Xu, F.J. Sanchez-Rivera, D.R. Liu & T. Jacks. Nat Biotechnol 42, 424-436 (2024).
  4. Nanomechanical action opens endo-lysosomal compartments. Y. Zhao, Z. Ye, D. Song, D. Wich, S. Gao, J. Khirallah & Q. Xu. Nat Commun 14, 6645 (2023).
  5. Gemini Amphiphiles: Robust Cytosolic Delivery of Therapeutic Biomacromolecules through Non-Endocytic Translocation Pathways. Y. Zhao, D. Wich & Q. Xu. ACS Cent Sci 9, 1266-1268 (2023).
  6. Lipidoid Artificial Compartments for Bidirectional Regulation of Enzyme Activity through Nanomechanical Action. Y. Zhao, S. Gao, D. Song, Z. Ye, R. Xu, Y. Luo & Q. Xu. J Am Chem Soc 145, 551-559 (2023).
  7. The mRNA Vaccine Revolution: COVID-19 Has Launched the Future of Vaccinology. Z. Ye, J. Harmon, W. Ni, Y. Li, D. Wich & Q. Xu. ACS Nano 17, 15231-15253 (2023).
  8. Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants. Z. Ye, S.R. Bonam, L.G.A. McKay, J.A. Plante, J. Walker, Y. Zhao, C. Huang, J. Chen, C. Xu, Y. Li, L. Liu, J. Harmon, S. Gao, D. Song, Z. Zhang, K.S. Plante, A. Griffiths, J. Chen, H. Hu & Q. Xu. Proc Natl Acad Sci U S A 120, e2311752120 (2023).
  9. Role of protein corona on nanoparticle-mediated organ and cell-targeted delivery. Q. Xu, S.K. Rajendrakumar & J. Khirallah. in Encyclopedia of Nanomaterials (First Edition) (eds. Y. Yin, Y. Lu & Y. Xia) 506-518 (Elsevier, Oxford, 2023).
  10. Introduction: Nanomaterials for biomedicine. Q. Xu & X. Gao. in Encyclopedia of Nanomaterials (First Edition) (eds. Y. Yin, Y. Lu & Y. Xia) 339 (Elsevier, Oxford, 2023).
  11. Correction to “Combinatorial Library of Lipidoids for In Vitro DNA Delivery”. S. Sun, M. Wang, S.A. Knupp, Y. Soto-Feliciano, X. Hu, D.L. Kaplan, R. Langer, D.G. Anderson & Q. Xu. Bioconjug Chem 34, 1348 (2023).
  12. A high-throughput approach of screening nanoparticles for targeted delivery of mRNA. J. Khirallah & Q. Xu. Cell Rep Methods 3, 100572 (2023).
  13. Clinical progress in genome-editing technology and in vivo delivery techniques. J. Khirallah, M. Eimbinder, Y. Li & Q. Xu. Trends Genet 39, 208-216 (2023).
  14. A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta. B. Carter, P. Huang, G. Liu, Y. Liang, P.J.C. Lin, B.H. Peng, L.G.A. McKay, A. Dimitrakakis, J. Hsu, V. Tat, P. Saenkham-Huntsinger, J. Chen, C. Kaseke, G.D. Gaiha, Q. Xu, A. Griffiths, Y.K. Tam, C.K. Tseng & D.K. Gifford. Front Immunol 14, 1135815 (2023).
  15. In Vitro Engineering Chimeric Antigen Receptor Macrophages and T Cells by Lipid Nanoparticle-Mediated mRNA Delivery. Z. Ye, J. Chen, X. Zhao, Y. Li, J. Harmon, C. Huang, J. Chen & Q. Xu. ACS Biomater Sci Eng 8, 722-733 (2022).
  16. The effects of protein corona on in vivo fate of nanocarriers. Q. Xiao, M. Zoulikha, M. Qiu, C. Teng, C. Lin, X. Li, M.A. Sallam, Q. Xu & W. He. Adv Drug Deliv Rev 186, 114356 (2022).
  17. Challenges in delivering therapeutic peptides and proteins: A silk-based solution. J. Wu, J.K. Sahoo, Y. Li, Q. Xu & D.L. Kaplan. J Control Release 345, 176-189 (2022).
  18. Engineering a Nano/Biointerface for Cell and Organ-Selective Drug Delivery. D. Song & Q. Xu. Langmuir 38, 9092-9098 (2022).
  19. Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis. M. Qiu, Y. Tang, J. Chen, R. Muriph, Z. Ye, C. Huang, J. Evans, E.P. Henske & Q. Xu. Proc Natl Acad Sci U S A 119(2022).
  20. Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins, and drugs. Y. Li, Z. Ye, H. Yang & Q. Xu. Acta Pharm Sin B 12, 2624-2639 (2022).
  21. Chapter Ten – Nonviral gene editing in cancer immunotherapy. Y. Li & Q. Xu. in Systemic Drug Delivery Strategies (eds. M.M. Amiji & L.S. Milane) 257-272 (Academic Press, 2022).
  22. Chemical Modification of Proteins and Their Intracellular Delivery Using Lipidoid Nanoparticles. Y. Li, Z. Glass & Q. Xu. in Methods Mol Biol, Vol. 2394 555-573 (2022).
  23. Intracellular Delivery of Antibodies for Selective Cell Signaling Interference. R.L. Hershman, Y. Li, F. Ma, Q. Xu & J.A. Van Deventer. ChemMedChem 17(2022).
  24. Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8(+) T cell response. J. Chen, Z. Ye, C. Huang, M. Qiu, D. Song, Y. Li & Q. Xu. Proc Natl Acad Sci U S A 119, e2207841119 (2022).
  25. Current Developments and Challenges of mRNA Vaccines. J. Chen, J. Chen & Q. Xu. Annu Rev Biomed Eng 24, 85-109 (2022).
  26. CRISPR/Cas9 ribonucleoprotein-mediated genome and epigenome editing in mammalian cells. H. Bloomer, J. Khirallah, Y. Li & Q. Xu. Adv Drug Deliv Rev 181, 114087 (2022).
  27. mRNA Delivery Using Bioreducible Lipidoid Nanoparticles Facilitates Neural Differentiation of Human Mesenchymal Stem Cells. X. Zhao, Z. Glass, J. Chen, L. Yang, D.L. Kaplan & Q. Xu. Advanced Healthcare Materials 10, 2000938 (2021).
  28. In Vivo Activation of Pro-Protein Therapeutics via Chemically Engineered Enzyme Cascade Reaction. X. Yang, J. Chang, Y. Jiang, Q. Xu, M. Wang & L. Mao. CCS Chemistry 3, 780-790 (2021).
  29. Study the lipidoid nanoparticle mediated genome editing protein delivery using 3D intestinal tissue model. T. Yang, H. Han, Y. Chen, L. Yang, R. Parker, Y. Li, D.L. Kaplan & Q. Xu. Bioact Mater 6, 3671-3677 (2021).
  30. Osteogenic effects of microRNA-335-5p/lipidoid nanoparticles coated on titanium surface. Q. Wang, X. Wang, P. Valverde, D. Murray, M.M. Dard, T. Van Dyke, Q. Xu, X. Xu, N. Karimbux, Q. Tu & J. Chen. Archives of Oral Biology 129, 105207 (2021).
  31. The NIH Somatic Cell Genome Editing program. K. Saha, E.J. Sontheimer, P.J. Brooks, M.R. Dwinell, C.A. Gersbach, D.R. Liu, S.A. Murray, S.Q. Tsai, R.C. Wilson, D.G. Anderson, A. Asokan, J.F. Banfield, K.S. Bankiewicz, G. Bao, J.W.M. Bulte, N. Bursac, J.M. Campbell, D.F. Carlson, E.L. Chaikof, Z.-Y. Chen, R.H. Cheng, K.J. Clark, D.T. Curiel, J.E. Dahlman, B.E. Deverman, M.E. Dickinson, J.A. Doudna, S.C. Ekker, M.E. Emborg, G. Feng, B.S. Freedman, D.M. Gamm, G. Gao, I.C. Ghiran, P.M. Glazer, S. Gong, J.D. Heaney, J.D. Hennebold, J.T. Hinson, A. Khvorova, S. Kiani, W.R. Lagor, K.S. Lam, K.W. Leong, J.E. Levine, J.A. Lewis, C.M. Lutz, D.H. Ly, S. Maragh, P.B. McCray, T.C. McDevitt, O. Mirochnitchenko, R. Morizane, N. Murthy, R.S. Prather, J.A. Ronald, S. Roy, S. Roy, V. Sabbisetti, W.M. Saltzman, P.J. Santangelo, D.J. Segal, M. Shimoyama, M.C. Skala, A.F. Tarantal, J.C. Tilton, G.A. Truskey, M. Vandsburger, J.K. Watts, K.D. Wells, S.A. Wolfe, Q. Xu, W. Xue, G. Yi & J. Zhou. Nature 592, 195-204 (2021).
  32. Developing Biodegradable Lipid Nanoparticles for Intracellular mRNA Delivery and Genome Editing. M. Qiu, Y. Li, H. Bloomer & Q. Xu. Acc Chem Res 54, 4001-4011 (2021).
  33. Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3. M. Qiu, Z. Glass, J. Chen, M. Haas, X. Jin, X. Zhao, X. Rui, Z. Ye, Y. Li, F. Zhang & Q. Xu. Proceedings of the National Academy of Sciences 118, e2020401118 (2021).
  34. Scaffold-mediated CRISPR-Cas9 delivery system for acute myeloid leukemia therapy. T.-C. Ho, H.S. Kim, Y. Chen, Y. Li, M.W. Lamere, C. Chen, H. Wang, J. Gong, C.D. Palumbo, J.M. Ashton, H.-W. Kim, Q. Xu, M.W. Becker & K.W. Leong. Science Advances 7, eabg3217 (2021).
  35. In situ cancer vaccination using lipidoid nanoparticles. J. Chen, M. Qiu, Z. Ye, T. Nyalile, Y. Li, Z. Glass, X. Zhao, L. Yang, J. Chen & Q. Xu. Science Advances 7(2021).
  36. Enhanced protein degradation by intracellular delivery of pre-fused PROTACs using lipid-like nanoparticles. J. Chen, M. Qiu, F. Ma, L. Yang, Z. Glass & Q. Xu. Journal of Controlled Release : Official Journal of the Controlled Release Society 330, 1244-1249 (2021).
  37. Preliminary Immunogenicity of a Pan-COVID-19 T Cell Vaccine in HLA-A*02:01 Mice. C. Brandon, C. Jinjin, K. Clarety, D. Alexander, D.G. Gaurav, X. Qiaobing & K.G. David. bioRxiv, 2021.2005.2002.442052 (2021).
  38. ImidazoleBased Synthetic Lipidoids for In Vivo mRNA Delivery into Primary T Lymphocytes. X. Zhao, J. Chen, M. Qiu, Y. Li, Z. Glass & Q. Xu. Angewandte Chemie International Edition 59, 20083-20089 (2020).
  39. The Construction of Biomimetic Cementum Through a Combination of Bioskiving and Fluorine-Containing Biomineralization. T. Yang, Y. Li, Y. Hong, L. Chi, C. Liu, Y. Lan, Q. Wang, Y. Yu, Q. Xu & W. Teng. Front Bioeng Biotechnol 8, 341 (2020).
  40. Efficient Delivery of Antisense Oligonucleotides Using Bioreducible Lipid Nanoparticles In Vitro and In Vivo. L. Yang, F. Ma, F. Liu, J. Chen, X. Zhao & Q. Xu. Mol Ther Nucleic Acids 19, 1357-1367 (2020).
  41. Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection. F. Ma, L. Yang, Z. Sun, J. Chen, X. Rui, Z. Glass & Q. Xu. Science Advances 6, eabb4429 (2020).
  42. In Vitro and In Vivo Study of Amphotericin B Formulation with Quaternized Bioreducible Lipidoids. F. Liu, L. Yang, Y. Li, A. Junier, F. Ma, J. Chen, H. Han, Z. Glass, X. Zhao, C.A. Kumamoto, H. Sang & Q. Xu. ACS Biomaterials Science & Engineering 6, 1064-1073 (2020).
  43. Combinatorial Library of Cyclic Benzylidene Acetal-Containing pH-Responsive Lipidoid Nanoparticles for Intracellular mRNA Delivery. Y. Li, R. Li, A. Chakraborty, R. Ogurlu, X. Zhao, J. Chen & Q. Xu. Bioconjug Chem 31, 1835-1843 (2020).
  44. Intracellular Antibody Delivery Mediated by Lipids, Polymers, and Inorganic Nanomaterials for Therapeutic Applications. Y. Li, P. Li, R. Li & Q. Xu. Advanced Therapeutics 3, 2000178 (2020).
  45. Protein and mRNA Delivery Enabled by CholesterylBased Biodegradable Lipidoid Nanoparticles. Y. Li, R. Jarvis, K. Zhu, Z. Glass, R. Ogurlu, P. Gao, P. Li, J. Chen, Y. Yu, Y. Yang & Q. Xu. Angewandte Chemie International Edition 59, 14957-14964 (2020).
  46. Ex vivo cell-based CRISPR/Cas9 genome editing for therapeutic applications. Y. Li, Z. Glass, M. Huang, Z.-Y. Chen & Q. Xu. Biomaterials 234, 119711 (2020).
  47. Developing chemically modified redox-responsive proteins as smart therapeutics. Q. Tang, J. Wang, Y. Jiang, M. Zhang, J. Chang, Q. Xu, L. Mao & M. Wang. Chemical Communications 55, 5163-5166 (2019).
  48. Nonviral Nanoparticles for CRISPR-Based Genome Editing: Is It Just a Simple Adaption of What Have Been Developed for Nucleic Acid Delivery? M. Qiu, Z. Glass & Q. Xu. Biomacromolecules 20, 3333-3339 (2019).
  49. Design of Silk-Elastin-Like Protein Nanoparticle Systems with Mucoadhesive Properties. Parker, Wu, McKay, Xu & Kaplan. Journal of Functional Biomaterials 10, 49 (2019).
  50. A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases. X. Ma, P. Zhou, A. Kugelmass, D. Toskic, M. Warner, L. Lee, T. Fogaren, A. Godara, M. Wang, Y. Li, L. Yang, Q. Xu & R.L. Comenzo. Gene Therapy 26, 187-197 (2019).
  51. Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles. J. Liu, J. Chang, Y. Jiang, X. Meng, T. Sun, L. Mao, Q. Xu & M. Wang. Advanced Materials 31, 1902575 (2019).
  52. Intracellular Delivery of His-Tagged Genome-Editing Proteins Enabled by Nitrilotriacetic Acid-Containing Lipidoid Nanoparticles. Y. Li, A.C. Li & Q. Xu. Advanced Healthcare Materials 8, e1800996 (2019).
  53. Combinatorial Library of Light-Cleavable Lipidoid Nanoparticles for Intracellular Drug Delivery. Y. Li, A. Chakraborty, J. Chen & Q. Xu. ACS Biomaterials Science & Engineering 5, 2391-2398 (2019).
  54. Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles. Y. Li, J. Bolinger, Y. Yu, Z. Glass, N. Shi, L. Yang, M. Wang & Q. Xu. Biomaterials Science 7, 596-606 (2019).
  55. Evaluation of an elastic decellularized tendonderived scaffold for the vascular tissue engineering application. S. Ghazanfari, K.A. Alberti, Q. Xu & A. Khademhosseini. Journal of Biomedical Materials Research Part A 107, 1225-1234 (2019).
  56. Integrating Combinatorial Lipid Nanoparticle and Chemically Modified Protein for Intracellular Delivery and Genome Editing. J. Chang, X. Chen, Z. Glass, F. Gao, L. Mao, M. Wang & Q. Xu. Acc Chem Res 52, 665-675 (2019).
  57. Polymer Amphiphiles for Photoregulated Anticancer Drug Delivery. V. Brega, F. Scaletti, X. Zhang, L.-S. Wang, P. Li, Q. Xu, V.M. Rotello & S.W. Thomas. ACS Applied Materials & Interfaces 11, 2814-2820 (2019).
  58. A novel Lipidoid-MicroRNA formulation promotes calvarial bone regeneration. L. Sui, M. Wang, Q. Han, L. Yu, L. Zhang, L. Zheng, J. Lian, J. Zhang, P. Valverde, Q. Xu, Q. Tu & J. Chen. Biomaterials 177, 88-97 (2018).
  59. Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins. Y. Li, T. Yang, Y. Yu, N. Shi, L. Yang, Z. Glass, J. Bolinger, I.J. Finkel, W. Li & Q. Xu. Biomaterials 178, 652-662 (2018).
  60. Rescued from the fate of neurological disorder. Y. Li, Z. Glass & Q. Xu. Nature Biomedical Engineering 2, 469-470 (2018).
  61. Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. G.Y. Koh, A. Kane, K. Lee, Q. Xu, X. Wu, J. Roper, J.B. Mason & J.W. Crott. Int J Cancer 143, 1797-1805 (2018).
  62. Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. X. Gao, Y. Tao, V. Lamas, M. Huang, W.-H. Yeh, B. Pan, Y.-J. Hu, J.H. Hu, D.B. Thompson, Y. Shu, Y. Li, H. Wang, S. Yang, Q. Xu, D.B. Polley, M.C. Liberman, W.-J. Kong, J.R. Holt, Z.-Y. Chen & D.R. Liu. Nature 553, 217-221 (2018).
  63. Shape Engineering Boosts Magnetic Mesoporous Silica Nanoparticle-Based Isolation and Detection of Circulating Tumor Cells. Z.-M. Chang, Z. Wang, D. Shao, J. Yue, H. Xing, L. Li, M. Ge, M. Li, H. Yan, H. Hu, Q. Xu & W.-F. Dong. ACS Appl Mater Interfaces 10, 10656-10663 (2018).
  64. Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival. B. Bahmani, M. Uehara, L. Jiang, F. Ordikhani, N. Banouni, T. Ichimura, Z. Solhjou, G.J. Furtmüller, G. Brandacher, D. Alvarez, U.H. von Andrian, K. Uchimura, Q. Xu, I. Vohra, O.A. Yilmam, Y. Haik, J. Azzi, V. Kasinath, J.S. Bromberg, M.M. McGrath & R. Abdi. J Clin Invest 128, 4770-4786 (2018).
  65. Hyper-Crosslinkers Lead to Temperature- and pH-Responsive Polymeric Nanogels with Unusual Volume Change. N. Zhou, X. Cao, X. Du, H. Wang, M. Wang, S. Liu, K. Nguyen, K. Schmidt-Rohr, Q. Xu, G. Liang & B. Xu. Angew Chem Int Ed Engl 56, 2623-2627 (2017).
  66. Pulling Cancer Cells Apart with a Net of Nanofibers. Q. Xu & C.I. Neufeld. Chem 2, 167-168 (2017).
  67. Janus Gold Nanoplatform for Synergetic Chemoradiotherapy and Computed Tomography Imaging of Hepatocellular Carcinoma. Z. Wang, D. Shao, Z. Chang, M. Lu, Y. Wang, J. Yue, D. Yang, M. Li, Q. Xu & W.-F. Dong. ACS Nano 11, 12732-12741 (2017).
  68. Hyaluronic acid modification of RNase A and its intracellular delivery using lipid-like nanoparticles. X. Wang, Y. Li, Q. Li, C.I. Neufeld, D. Pouli, S. Sun, L. Yang, P. Deng, M. Wang, I. Georgakoudi, S. Tang & Q. Xu. Journal of Controlled Release : Official Journal of the Controlled Release Society 263, 39-45 (2017).
  69. Non-viral delivery of genome-editing nucleases for gene therapy. M. Wang, Z.A. Glass & Q. Xu. Gene Therapy 24, 144-150 (2017).
  70. Active Targeting of the Nucleus Using Nonpeptidic Boronate Tags. R. Tang, M. Wang, M. Ray, Y. Jiang, Z. Jiang, Q. Xu & V.M. Rotello. Journal of the American Chemical Society 139, 8547-8551 (2017).
  71. Parabacteroides distasonis attenuates colonic inflammation and prevents tumor formation in azoxymethane-treated high-fat diet-fed mice. G.Y. Koh, A.V. Kane, K. Lee, Q. Xu, X. Wu, J.B. Mason & J.W. Crott. The FASEB Journal 31, 435.432-435.432 (2017).
  72. Nanoparticles for CRISPR-Cas9 delivery. Z. Glass, Y. Li & Q. Xu. Nature Biomedical Engineering 1, 854-855 (2017).
  73. Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles. M. Wang, J.A. Zuris, F. Meng, H. Rees, S. Sun, P. Deng, Y. Han, X. Gao, D. Pouli, Q. Wu, I. Georgakoudi, D.R. Liu & Q. Xu. Proceedings of the National Academy of Sciences of the United States of America 113, 2868-2873 (2016).
  74. A toolkit of thread-based microfluidics, sensors, and electronics for 3D tissue embedding for medical diagnostics. P. Mostafalu, M. Akbari, K.A. Alberti, Q. Xu, A. Khademhosseini & S.R. Sonkusale. Microsyst Nanoeng 2, 16039 (2016).
  75. Nanostructured Tendon-Derived Scaffolds for Enhanced Bone Regeneration by Human Adipose-Derived Stem Cells. E. Ko, K. Alberti, J.S. Lee, K. Yang, Y. Jin, J. Shin, H.S. Yang, Q. Xu & S.-W. Cho. ACS Appl Mater Interfaces 8, 22819-22829 (2016).
  76. A rodent model for non-surgical sterilization using an antibody-guided lipid nanoparticle cytotoxin delivery system Q.X. K. Meadows, S. Ayresa Clinical Theriogenology 8, 3 (2016).
  77. Chemically Engineered Nanoparticle-Protein Interface for Real-Time Cellular Oxidative Stress Monitoring. Y. Jiang, M. Wang, J. Hardie, G.Y. Tonga, M. Ray, Q. Xu & V.M. Rotello. Small 12, 3775-3779 (2016).
  78. The matrix reloaded: the evolution of regenerative hydrogels. E. Jabbari, J. Leijten, Q. Xu & A. Khademhosseini. Materials Today 19, 190-196 (2016).
  79. Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes. X. Hu, M.J. Feeney, E. McIntosh, J. Mullahoo, F. Jia, Q. Xu & S.W. Thomas. ACS Appl Mater Interfaces 8, 23517-23522 (2016).
  80. Intracellular delivery of the PTEN protein using cationic lipidoids for cancer therapy. S.A. Altınoğlu, M. Wang, K.Q. Li, Y. Li & Q. Xu. Biomaterials Science 4, 1773-1780 (2016).
  81. Biocompatibility and degradation of tendon-derived scaffolds. K.A. Alberti & Q. Xu. Regen Biomater 3(2016).
  82. In Vivo Peripheral Nerve Repair Using Tendon-Derived Nerve Guidance Conduits. K.A. Alberti, C.I. Neufeld, J. Wang & Q. Xu. ACS Biomaterials Science & Engineering 2, 937-945 (2016).
  83. Integrating Protein Engineering and Bioorthogonal Click Conjugation for Extracellular Vesicle Modulation and Intracellular Delivery. M. Wang, S. Altinoglu, Y.S. Takeda & Q. Xu. PloS One 10, e0141860 (2015).
  84. Neuronal Differentiation of Human Mesenchymal Stem Cells Using Exosomes Derived from Differentiating Neuronal Cells. Y.S. Takeda & Q. Xu. PloS One 10, e0135111 (2015).
  85. Synthetic and nature-derived lipid nanoparticles for neural regeneration. Y.S. Takeda & Q. Xu. Neural Regen Res 10, 689-690 (2015).
  86. Biophysical Methods for the Studies of Protein-Lipid/Surfactant Interactions. S. Sun, C.I. Neufeld, R.F. Latypov, B. Perez-Ramirez & Q. Xu. in Recent Progress in Colloid and Surface Chemistry with Biological Applications, Vol. 1215 355-375 (American Chemical Society, 2015).
  87. Emerging therapies targeting intra-organ inflammation in transplantation. Z. Solhjou, H. Athar, Q. Xu & R. Abdi. Am J Transplant 15, 305-311 (2015).
  88. Carbonic anhydrase generates a pH gradient in Bombyx mori silk glands. L.J. Domigan, M. Andersson, K.A. Alberti, M. Chesler, Q. Xu, J. Johansson, A. Rising & D.L. Kaplan. Insect Biochem Mol Biol 65, 100-106 (2015).
  89. Combinatorial Cationic Lipid Library Synthesis for Drug Delivery. S. Altinoglu & Q. Xu. in Perspectives in Micro- and Nanotechnology for Biomedical Applications 125-152 (IMPERIAL COLLEGE PRESS, 2015).
  90. Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications. S. Altinoglu, M. Wang & Q. Xu. Nanomedicine (Lond) 10, 643-657 (2015).
  91. Laminar Tendon Composites with Enhanced Mechanical Properties. K.A. Alberti, J.-Y. Sun, W.R. Illeperuma, Z. Suo & Q. Xu. J Mater Sci 50, 2616-2625 (2015).
  92. Hydrophobic drug-triggered self-assembly of nanoparticles from silk-elastin-like protein polymers for drug delivery. X.-X. Xia, M. Wang, Y. Lin, Q. Xu & D.L. Kaplan. Biomacromolecules 15, 908-914 (2014).
  93. High Throughput Screening of Dynamic Silk-Elastin-Like Protein Biomaterials. Q. Wang, X. Xia, W. Huang, Y. Lin, Q. Xu & D.L. Kaplan. Adv Funct Mater 24, 4303-4310 (2014).
  94. Reactive oxygen species-responsive protein modification and its intracellular delivery for targeted cancer therapy. M. Wang, S. Sun, C.I. Neufeld, B. Perez-Ramirez & Q. Xu. Angew Chem Int Ed Engl 53, 13444-13448 (2014).
  95. Enhanced intracellular siRNA delivery using bioreducible lipid-like nanoparticles. M. Wang, K. Alberti, A. Varone, D. Pouli, I. Georgakoudi & Q. Xu. Advanced Healthcare Materials 3, 1398-1403 (2014).
  96. Combinatorially designed lipid-like nanoparticles for intracellular delivery of cytotoxic protein for cancer therapy. M. Wang, K. Alberti, S. Sun, C.L. Arellano & Q. Xu. Angew Chem Int Ed Engl 53, 2893-2898 (2014).
  97. Fabrication of 2D and 3D constructs from reconstituted decellularized tissue extracellular matrices. Y.S. Takeda & Q. Xu. J Biomed Nanotechnol 10, 3631-3637 (2014).
  98. Genetically programmable thermoresponsive plasmonic gold/silk-elastin protein core/shell nanoparticles. Y. Lin, X. Xia, M. Wang, Q. Wang, B. An, H. Tao, Q. Xu, F. Omenetto & D.L. Kaplan. Langmuir : the ACS Journal of Surfaces and Colloids 30, 4406-4414 (2014).
  99. Pericellular hydrogel/nanonets inhibit cancer cells. Y. Kuang, J. Shi, J. Li, D. Yuan, K.A. Alberti, Q. Xu & B. Xu. Angew Chem Int Ed Engl 53, 8104-8107 (2014).
  100. All electronic approach for high-throughput cell trapping and lysis with electrical impedance monitoring. S.K. Ameri, P.K. Singh, M.R. Dokmeci, A. Khademhosseini, Q. Xu & S.R. Sonkusale. Biosens Bioelectron 54, 462-467 (2014).
  101. The behavior of neuronal cells on tendon-derived collagen sheets as potential substrates for nerve regeneration. K.A. Alberti, A.M. Hopkins, M.D. Tang-Schomer, D.L. Kaplan & Q. Xu. Biomaterials 35, 3551-3557 (2014).
  102. DOPE facilitates quaternized lipidoids (QLDs) for in vitro DNA delivery. S. Sun, M. Wang, K.A. Alberti, A. Choy & Q. Xu. Nanomedicine 9, 849-854 (2013).
  103. Slicing, stacking and rolling: fabrication of nanostructured collagen constructs from tendon sections. K.A. Alberti & Q. Xu. Advanced Healthcare Materials 2, 817-821 (2013).
  104. A combinatorial library of unsaturated lipidoids for efficient intracellular gene delivery. M. Wang, S. Sun, K.A. Alberti & Q. Xu. ACS Synth Biol 1, 403-407 (2012).
  105. Combinatorial library of lipidoids for in vitro DNA delivery. S. Sun, M. Wang, S.A. Knupp, Y. Soto-Feliciano, X. Hu, D.L. Kaplan, R. Langer, D.G. Anderson & Q. Xu. Bioconjug Chem 23, 135-140 (2012).
  106. Microfabrication technologies for oral drug delivery. S. Sant, S.L. Tao, O.Z. Fisher, Q. Xu, N.A. Peppas & A. Khademhosseini. Advanced Drug Delivery Reviews 64, 496-507 (2012).
  107. Staining and etching: a simple method to fabricate inorganic nanostructures from tissue slices. X. Dai, R. Schalek & Q. Xu. Adv Mater 24, 370-374 (2012).
  108. Patterning nanoparticles in a three-dimensional matrix using an electric-field-assisted gel transferring technique. X. Dai, S.A. Knupp & Q. Xu. Langmuir : the ACS Journal of Surfaces and Colloids 28, 2960-2964 (2012).
  109. BIOINSPIRED FABRICATION OF NANOSTRUCTURES FROM TISSUE SLICES. K. Alberti & Q. Xu. in Handbook of Biomimetics and Bioinspiration, Vol. Volumes 9 1-16 (WORLD SCIENTIFIC, 2012).
  110. Tunable self-assembly of genetically engineered silk–elastin-like protein polymers. X.-X. Xia, Q. Xu, X. Hu, G. Qin & D.L. Kaplan. Biomacromolecules 12, 3844-3850 (2011).
  111. Nanostructured substrate fabricated by sectioning tendon using a microtome for tissue engineering. X. Dai & Q. Xu. Nanotechnology 22, 494008 (2011).
  112. An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation. B. Huo, X.L. Lu, K.D. Costa, Q. Xu & X.E. Guo. Cell Calcium 47, 234-241 (2010).
  113. Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. H. Cheng, C.J. Kastrup, R. Ramanathan, D.J. Siegwart, M. Ma, S.R. Bogatyrev, Q. Xu, K.A. Whitehead, R. Langer & D.G. Anderson. ACS Nano 4, 625-631 (2010).
  114. Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery. Q. Xu, M. Hashimoto, T.T. Dang, T. Hoare, D.S. Kohane, G.M. Whitesides, R. Langer & D.G. Anderson. Small 5, 1575-1581 (2009).
  115. Nanoskiving: a novel method for nanofabrication and its applications in nanophotonics. X. Qiaobing & M.W. George. in Proc.SPIE, Vol. 7205 72050P (2009).
  116. Microfabrication of homogenous, asymmetric cell-laden hydrogel capsules. T.T. Dang, Q. Xu, K.M. Bratlie, E.S. O’Sullivan, X.Y. Chen, R. Langer & D.G. Anderson. Biomaterials 30, 6896-6902 (2009).
  117. Lipid-like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells. S.W. Cho, M. Goldberg, S.M. Son, Q. Xu, F. Yang, Y. Mei, S. Bogatyrev, R. Langer & D.G. Anderson. Adv Funct Mater 19, 3112-3118 (2009).
  118. Nanoskiving: a new method to produce arrays of nanostructures. Q. Xu, R.M. Rioux, M.D. Dickey & G.M. Whitesides. Acc Chem Res 41, 1566-1577 (2008).
  119. Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation. N. Xia, C.K. Thodeti, T.P. Hunt, Q. Xu, M. Ho, G.M. Whitesides, R. Westervelt & D.E. Ingber. Faseb j 22, 1649-1659 (2008).
  120. Cell-compatible, multicomponent protein arrays with subcellular feature resolution. Y. Mei, C. Cannizzaro, H. Park, Q. Xu, S.R. Bogatyrev, K. Yi, N. Goldman, R. Langer & D.G. Anderson. Small 4, 1600-1604 (2008).
  121. Fluid Flow Induced Calcium Response in Bone Cell Network. B. Huo, X.L. Lu, C.T. Hung, K.D. Costa, Q. Xu, G.M. Whitesides & X.E. Guo. Cell Mol Bioeng 1, 58-66 (2008).
  122. Delivery of small interfering RNA for inhibition of endothelial cell apoptosis by hypoxia and serum deprivation. S.W. Cho, L. Hartle, S.M. Son, F. Yang, M. Goldberg, Q. Xu, R. Langer & D.G. Anderson. Biochem Biophys Res Commun 376, 158-163 (2008).
  123. Fabrication of complex metallic nanostructures by nanoskiving. Q. Xu, R.M. Rioux & G.M. Whitesides. ACS Nano 1, 215-227 (2007).
  124. Fabrication of large-area patterned nanostructures for optical applications by nanoskiving. Q. Xu, J. Bao, R.M. Rioux, R. Perez-Castillejos, F. Capasso & G.M. Whitesides. Nano Lett 7, 2800-2805 (2007).
  125. Fabrication of high-aspect-ratio metallic nanostructures using nanoskiving. Q. Xu, R. Perez-Castillejos, Z. Li & G.M. Whitesides. Nano Lett 6, 2163-2165 (2006).
  126. Surface plasmon resonances of free-standing gold nanowires fabricated by nanoskiving. Q. Xu, J. Bao, F. Capasso & G.M. Whitesides. Angew Chem Int Ed Engl 45, 3631-3635 (2006).
  127. Core-shell and segmented polymer-metal composite nanostructures. M. Lahav, E.A. Weiss, Q. Xu & G.M. Whitesides. Nano Lett 6, 2166-2171 (2006).
  128. Intracellular calcium waves in bone cell networks under single cell nanoindentation. X.E. Guo, E. Takai, X. Jiang, Q. Xu, G.M. Whitesides, J.T. Yardley, C.T. Hung, E.M. Chow, T. Hantschel & K.D. Costa. Mol Cell Biomech 3, 95-107 (2006).
  129. Approaching zero: using fractured crystals in metrology for replica molding. Q. Xu, B.T. Mayers, M. Lahav, D.V. Vezenov & G.M. Whitesides. J Am Chem Soc 127, 854-855 (2005).
  130. A general method for patterning gradients of biomolecules on surfaces using microfluidic networks. X. Jiang, Q. Xu, S.K. Dertinger, A.D. Stroock, T.M. Fu & G.M. Whitesides. Anal Chem 77, 2338-2347 (2005).
  131. New approaches to nanofabrication: molding, printing, and other techniques. B.D. Gates, Q. Xu, M. Stewart, D. Ryan, C.G. Willson & G.M. Whitesides. Chem Rev 105, 1171-1196 (2005).
  132. Fabrication of thin, metallic films along the sidewalls of a topographically patterned stamp and their application in charge printing. T. Cao, Q. Xu, A. Winkleman & G.M. Whitesides. Small 1, 1191-1195 (2005).
  133. Fabrication of Free-Standing Metallic Pyramidal Shells. Q. Xu, I. Tonks, M.J. Fuerstman, J.C. Love & G.M. Whitesides. Nano Letters 4, 2509-2511 (2004).
  134. Fabrication of metal structures with nanometer-scale lateral dimensions by sectioning using a microtome. Q. Xu, B.D. Gates & G.M. Whitesides. J Am Chem Soc 126, 1332-1333 (2004).
  135. Shear patterning of microdominos: a new class of procedures for making micro- and nanostructures. B.D. Gates, Q. Xu, V.R. Thalladi, T. Cao, T. Knickerbocker & G.M. Whitesides. Angew Chem Int Ed Engl 43, 2780-2783 (2004).
  136. UNCONVENTIONAL NANOFABRICATION. B.D. Gates, Q. Xu, J.C. Love, D.B. Wolfe & G.M. Whitesides. Annual Review of Materials Research 34, 339-372 (2004).
  137. Supramolecular research by single molecule force Spectroscopy. W. Zhang, Q. Xu, C. Wang & X. Zhang. Macromolecular Symposia 195, 109-114 (2003).
  138. Oxygen Bridge Inhibits Conformational Transition of 1,4-Linked α-d-Galactose Detected by Single-Molecule Atomic Force Microscopy. Q. Xu, W. Zhang & X. Zhang. Macromolecules 35, 871-876 (2002).
  139. Single-Molecule Force Spectroscopy on Carrageenan by Means of AFM. Q. Xu, S. Zou, W. Zhang & X. Zhang. Macromolecular Rapid Communications 22, 1163-1167 (2001).
  140. Single-Molecule Force Spectroscopy on Bombyx mori Silk Fibroin by Atomic Force Microscopy. W. Zhang, Q. Xu, S. Zou, H. Li, W. Xu, X. Zhang, Z. Shao, M. Kudera & H.E. Gaub. Langmuir 16, 4305-4308 (2000).
keywords:XULAB AT TUFTS BME XULAB AT TUFTS BME